YERXA, BENJAMIN R.,DOUGLASS, JAMES G., III,SHAVER, SAMMY RAY,PETERSON, WARD M.,BROWN, EDWARD G.,CREAN, CHRISTOPHER S.
申请号：
CA2477241
公开号：
CA2477241C
申请日:
2003.02.27
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The present invention relates to mononucleoside phosphate compoundsthat havethebenefits of a dinucleotide pharmaceutical. These mononucleoside phosphates canbemade from a mononucleotide that has been modified byattaching a degradationresistantsubstituent on the terminal phosphate of apolyphosphate mononucleotide. Byattachingthis degradation resistant substituent, the stability from degradation matchesor exceedsthose of certain dinucleotides.(see formula I)
