PLATINUM COMPOUND HAVING AMINO OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARTION METHOD THEREOF, AND USE THEREOF

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专利权人:

发明人:

Xiaoping Chen,Zejun Gao,Xiaoping Meng,Shouming Wen,Yashi Yan,Feng Zhao

申请号：

US14345384

公开号：

US20140349985A1

申请日:

2012.09.18

申请国别(地区):

US

年份:

2014

代理人:

摘要：

Disclosed are a category of platinum compounds having amino- or alkylamino-containing succinato derivatives as leaving group, or pharmaceutically acceptable salts thereof, preparation method thereof, and medicinal compositions containing the compounds. Also disclosed is a use of the compounds in treating cell proliferative diseases, especially cancers. The platinum compounds of the present invention have high water solubility and small toxic side effect.

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