Vegf/dll4 binding agents and uses thereof

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专利权人:

ONCOMED PHARMACEUTICALS INC.

发明人:

GURNEY AUSTIN L.,SATO AARON KEN,BOND CHRISTOPHER JOHN

申请号：

NZ62372412

公开号：

NZ623724A

申请日:

2012.09.24

申请国别(地区):

NZ

年份:

2016

代理人:

摘要：

Disclosed is a bispecific antibody comprising: a) a first antigen-binding site that specifically binds human vascular endothelial growth factor (VEGF), and b) a second antigen-binding site that specifically binds human delta-like 4 ligand (DLL4), comprising the CDRs of the sequences as defined in the specification. Also disclosed is its use in treating cancer.

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