A sanitization system includes a sanitization manager and one or more sanitization stations. The sanitization manager monitors portable devices (PDs), and schedules sanitization operations for the PDs based on, inter alia, a sanitization policy. The sanitization policy may require a PD to be sanitized based on a time elapsed since a last time the PD was sanitized and/or potential contamination of the PD (e.g., based on PD usage, location, patient exposure, and/or the like). The sanitization stations may be configured to notify the sanitization manager of sanitization operations performed on respective PDs.