Liming Huang,Song Liu,Elizabeth A. Lunney,Simon P. Planken
申请号:
US13204741
公开号:
US20120035194A1
申请日:
2011.08.08
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to compounds of formula (I),or a pharmaceutically acceptable salt or solvate thereof, wherein: R1, R2, Z1, t, and ring A are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and methods of treating a condition that is mediated by the modulation of JNK, such as diabetes, the method comprising administering to a mammal an effective amount of a compound of formula (I).