A breaker device for acting onto a closure element (40) of a medical tubing (4) comprises: a drive arrangement (2) having a drive device (20), a drive element (23) driven by the drive device (20) and at least one locking element (22A, 22B), and a breaker module (3) which is arrangeable on the drive arrangement (2). The breaker module (3) comprises a housing (30), a movable part (31) movably arranged on the housing (30), a breaking element (315) for acting onto the closure element (40) of the tubing (4) and a locking mechanism (32A, 32B). The breaker module (3) in an attached state is placed on the drive arrangement (2) and is locked to the drive arrangement (2) via the locking mechanism (32A, 32B) engaging with the at least one locking element (22A, 22B), the drive element (23) being in operative connection with the movable part (31) in the attached state such that a movement of the drive element (23) causes the movable part (31) to move for actuating the breaking element (315). The breaker module (3) is releasable from the drive arrangement (2) by disengaging the locking mechanism (32A, 32B) from the at least one locking element (22A, 22B). Herein, the locking mechanism comprises at least one actuation member (32A, 32B) which is displaceable between a first position and a second position with respect to the housing (30), wherein the at least one actuation member (32A, 32B) is constituted to act, in the first position, onto the movable part (31) to force the movable part (31) into a position in which the movable part (31) can be brought into operative connection with the drive element (20) when arranging the breaker module (3) on the drive arrangement (2), and to engage, in the second positon, with the at least one locking element (22A, 22B) of the drive arrangement (2) when the breaker module (3) is in the attached state.
