Dane Goff,Donald Payan,Rajinder Singh,Simon Shaw,David Carroll,Yasumichi Hitoshi
申请号:
US14325766
公开号:
US09266856B2
申请日:
2014.07.08
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Disclosed are substituted pyridine compounds as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structurewherein E, J, T, the ring system denoted by “B”, T, R3, R4, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.