Japanese Foundation for Cancer Research;Research Foundation of the City University of New York
发明人:
Hiroshi Matsui,Kiyotaka Shiba,Min A. Kang
申请号：
US16436331
公开号：
US20190316163A1
申请日:
2019.06.10
申请国别(地区):
US
年份:
2019
代理人:
摘要：
A method for enhancing extracellular vesicle production is described. A peptide that induces polymer formation is incubated with a cell culture which results in enhanced EV production. The peptide penetrates the cells and subsequently polymerizes upon exposure to enzymes (e.g. phosphatase) within the cell. The cells that contain the newly formed polymers have an increased production of EVs. These EVs can be harvested using centrifugation techniques.
