Thomas H. Marsilje,Wenshuo Lu,Bei Chen,Xiaohui He,Badry Bursulaya,Christian Cho-Hua Lee
申请号:
US12675379
公开号:
US08440681B2
申请日:
2008.08.27
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention provides novel pyrimidine derivatives of formula (1) and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of insulin-like growth factor (IGF-1R) or anaplastic lymphoma kinase (ALK).