The present invention relates to a dermal filler injection compositions, include porous biodegradable particle and water-soluble natural polymer. According to the present invention, dermal filler injection composition significantly increases collagen content and tissue repair function, pass through the optimized combination of (1) content of porous biodegradable particle, (2) cross linkage ratio of hyaluronic acid, and crosslinking hyaluronic acid and purified water a kind of mixture (3) concentration.Copyright KIPO 2017