Hong Myung Lee;Leo R. Takaoka;Tianlin Xu;Brian S. Freeze;Masaaki Hirose;Todd B. Sells;Stepan Vyskocil;Zhan Shi
发明人:
Brian S. Freeze,Masaaki Hirose,Hong Myung Lee,Todd B. Sells,Zhan Shi,Leo R. Takaoka,Stepan Vyskocil,Tianlin Xu
申请号:
US13272413
公开号:
US20120214794A1
申请日:
2011.10.13
申请国别(地区):
US
年份:
2012
代理人:
摘要:
This invention provides compounds of formula I-A or I-B:wherein HY, G1, G2, R2, R12, W1, W2, n, and Ring A are as described in the specification. The compounds are inhibitors of PI3K and/or mTor and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.