ANTICORPS MONOCLONAL ANTI-PD-1, COMPOSITION PHARMACEUTIQUE ET UTILISATION DE CELUI-CI

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专利权人:

INC.;AKESO BIOPHARMA

发明人:

LI, BAIYONG,XIA, YU,WANG, ZHONGMIN MAXWELL,ZHANG, PENG

申请号：

CA3034849

公开号：

CA3034849A1

申请日:

2017.08.22

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

An anti-PD1 (programmed cell death 1) monoclonal antibody or an antigen-binding fragment thereof, a pharmaceutical composition thereof and use thereof. The heavy chain variable region of the monoclonal antibody comprises CDRs (complementary determining region) of amino acid sequences as shown in SEQ ID NO:9-11； and/or the light chain variable region of the monoclonal antibody comprises CDRs of amino acid sequences as shown in SEQ ID NO:12-14. The monoclonal antibody can bind to PD1 specifically, relieve immunosuppression of PD1 on an organism specifically and activate T lymphocytes.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/