Xiangdong QU,Qiyue HU,Shaoyu XU,Dongbing CUI,Houcong JIN,Weikang TAO,Lianshan ZHANG,Guoqing CAO,Piaoyang SUN
申请号：
US15775598
公开号：
US20180334504A1
申请日:
2016.11.02
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to a PD-L1 antibody, antigen-binding fragments, and medical application thereof. Further, the present invention relates to chimeric antibodies and humanized antibodies comprising the CDR regions of the present PD-L1 antibody, as well as a pharmaceutical composition comprising the present PD-L1 antibody and the antigen-binding fragments thereof, and their use as anti-cancer drugs. In particular, the present invention relates to a humanized PD-L1 antibody and its use in preparation of a medicament for the treatment of PD-L1 mediated disease or disorder.
