DIAZASPIROALKANEONE-SUBSTITUTED OXAZOLE DERIVATIVES AS SPLEEN TYROSINE KINASE INHIBITORS

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专利权人:

AB SCIENCE

发明人:

Abdellah BENJAHAD,Jason MARTIN,Claire SCHALON,Didier PEZ,Emmanuel CHEVENIER,Franck SANDRINELLI,Willy PICOUL,Alain MOUSSY

申请号：

US15128743

公开号：

US20180179195A1

申请日:

2015.03.23

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention is concerned with substituted oxazole derivatives that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant protein kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, autoimmune, allergic, and degenerative disorders. In particular, the presently disclosed compounds are Syk inhibitors.

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