AGENT FOR INHIBITING OR IMPROVING DECREASE OF LORICRIN, TRANSGLUTAMINASE-3 ACTIVATOR, AND AGENT FOR PROMOTING FORMATION OF SKIN HORNY CELL LAYER CORNIFIED ENVELOPE OR FOR STRENGTHENING STRUCTURE OF SKIN HORNY CELL LAYER CORNIFIED ENVELOPE
The present invention relates to: an agent for inhibiting or improving the decrease of loricrin in a cornified envelope of a horny cell layer of the skin, a transglutaminase-3 activator, and an agent for promoting the formation of a cornified envelope of a horny cell layer of the skin or for strengthening the structure of a cornified envelope of a horny cell layer of the skin, each of which contains sphingomyelin as an active ingredient a composition and a food or beverage. According to the present invention, it becomes possible to inhibit or improve the decrease of loricrin in a cornified envelope of a horny cell layer of the skin, and it also becomes possible to activate transglutaminase-3 in a cornified envelope of a horny cell layer of the skin. Therefore, it becomes possible to promote the formation of a cornified envelope of a horny cell layer of the skin and strengthen the structure of a cornified envelope of a horny cell layer of the skin. Due to these effects, the deterioration of a barrier function of skin can be prevented, inhibited or improved in a safe, simple and economically advantageous manner.La présente invention concerne : un agent pour inhiber ou améliorer la diminution de loricrine dans une enveloppe cornée dune couche de cellule morte de la peau, un activateur de transglutaminase-3, et un agent pour favoriser la formation dune enveloppe cornée dune couche de cellule morte de la peau ou pour renforcer la structure dune enveloppe cornée dune couche de cellule morte de la peau, dont chacun contient de la sphingomyéline comme principe actif une composition et un aliment ou une boisson. Selon la présente invention, il devient possible dinhiber ou daméliorer la diminution de loricrine dans une enveloppe cornée dune couche de cellule morte de la peau, et il devient également possible dactiver la transglutaminase-3 dans une enveloppe cornée dune couche de cellule morte de la peau. Par conséquent, il devient possible de favoriser la formation dune env