Mark Anthony Fernance Kendall,Stefano Meliga,Alexandra Christina Isabelle Depelsenaire,Michael Lawrence Crichton,Christopher Flaim
申请号：
US14351499
公开号：
US20140257188A1
申请日:
2012.10.12
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A device for delivery of material to a biological subject, the device including a base and a number of projections extending from the base, each projection including a tip for penetrating tissue of the biological subject, at least a portion of at least one of the projections being coated with a non-liquid coating including the material. At least the tip of at least one of the coated projections may have a convex effective profile. The device may be for delivery of material to a dermal layer of the biological subject. In another aspect an applicator for applying the device to the biological subject applies a preload force to the tissue such that the force at least partially compresses a subcutaneous tissue layer of the biological subject prior to application of the device, and applies the device with a predetermined velocity, wherein tissue stiffness is maintained and/or the projections penetrate the tissue to a predetermined depth.
