compound； 4- (3,5-dichloropyridin-4-ylamino) -7-methoxy-8- (6- (4-methylpiperazin-1-yl) hexyloxy) quinolin-2 (1h) -one, or a salt thereof； 4- (3,5-dichloropyridin-4-ylamino) -7-methoxy-8- (6-morpholinhexyloxy) quinolin-2 (1h) -one, or a salt thereof； pharmaceutical composition； ophthalmic pharmaceutical composition； pde4 inhibition method

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专利权人:

KALYPSYS; INC

发明人:

ANDREW K. SHIAU,CLAY BEAUREGARD,DANIELA A. GAMACHE,DAVID J THOMAS,JOHN M. YANNI,MARK R. HELLBERG,STEVEN P. GOVEK,STEWART A. NOBLE

申请号：

BR112012003738

公开号：

BR112012003738A2

申请日:

2010.08.19

申请国别(地区):

BR

年份:

2019

代理人:

摘要：

The present invention relates to compounds and methods which may be useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of inflammatory diseases and other diseases involving elevated levels of cytokines and proinflammatory mediators.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/