The invention provides a method for preparing a mesalazine enteric coated tablet comprising: (i) granulating a composition comprising mesalazine, a pharmaceutically acceptable salt, or ester thereof, into mesalazine granulates； (ii) tabletting a core composition comprising the mesalazine granulates obtained in (i) to obtain a tablet core； (iii) coating the tablet core obtained in (ii) with at least an enteric coating； where the tablet core hardness is controlled to be comprised between 80 N and 105 N.
