Hyman Chaim Birnboim,Lindsay Pozza,Carlos Alberto Merino Hernandez,Evgueni Vladimirovitch Doukhanine
申请号:
US15124060
公开号:
US10435735B2
申请日:
2015.03.06
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Methods, compositions, and kits for stabilizing both human and microbial deoxyribonucleic acid (DNA) present in complex biological samples, such as feces, are disclosed. In particular, aqueous compositions for stabilizing DNA contained in biological samples at ambient temperature are disclosed, together with associated methods and kits using same. In one aspect, the compositions comprise a chelating agent present at a concentration of at least about 150 mM, and the composition has a pH of at least about 9.5.