KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY;한국생산기술연구원
发明人:
YU, Byung Jo,유병조,JANG, Ji Yeon,장지연,JANG, In Seung,장인승
申请号：
KRKR2019/012093
公开号：
WO2020/060202A1
申请日:
2019.09.18
申请国别(地区):
KR
年份:
2020
代理人:
摘要：
The present invention pertains to an expression cassette for preparing thymulin or argireline, and a use thereof, and specifically to: an expression cassette for preparing thymulin or argireline, the expression cassette containing a polynucleotide sequence encoding thymulin or argireline, the polynucleotide sequence being operably linked with a high-level secretory signal sequence and a promoter sequence that can be expressed in yeast； an expression vector comprising the expression cassette； a transformant comprising the expression vector； a method for preparing thymulin or argireline using the transformant； a hair-loss preventing or hair-growth promoting cosmetic composition and quasi-drug composition containing thymulin prepared by the method； and an anti-wrinkle cosmetic composition and quasi-drug composition containing argireline prepared by the method. High-purity thymulin or argireline can be prepared in large amounts at low cost by using the expression cassette for preparing thymulin or argireline, the expression vector, and the transformant comprising the expression vector of the present invention. Thymulin prepared according to the present invention has an excellent hair-loss preventing and hair-growth promoting effect, and can thus be widely used in many industries, such as the hair-loss preventing or hair-growth promoting cosmetic materials and quasi-drug industries. In addition, Argireline prepared according to the present invention has an excellent anti-wrinkle effect and very low toxicity, and can thus be widely used in many industries, such as the anti-wrinkle cosmetic materials and quasi-drug industries.La présente invention concerne une cassette d'expression pour la préparation de thymuline ou d'argireline, ainsi que son utilisation et plus précisément : une cassette d'expression pour la préparation de thymuline ou d'argireline, la cassette d'expression contenant une séquence polynucléotidique codant pour thymuline ou argireline, la séquence polynuc
