ANTIBODIES AND ANTIBODY-DRUG CONJUGATES SPECIFIC FOR CD123 AND USES THEREOF

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专利权人:

Pfizer Inc.

发明人:

Manoj Baburao CHARATI,Yoon-Chi HAN,Madan KATRAGADDA,Nicole Melissa PICHÉ-NICHOLAS,Lawrence Nathan TUMEY

申请号：

US16758124

公开号：

US20200283536A1

申请日:

2018.10.16

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention provides antibodies that specifically bind to CD123. The invention further relates to immunoconjugates (e.g., antibody-drug conjugates, or ADCs) comprising such antibodies, antibody encoding nucleic acids, and methods of obtaining such antibodies. The invention further relates to therapeutic methods for use of these antibodies and ADCs for the treatment of a condition associated with cells expressing CD123 (e.g., cancer or autoimmune disease).

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