#$%^&*AU2014202357B220160526.pdf#####ABSTRACT A nonaqueous, extrudable composition includes at least one thermoplastic polymer in an amount of more than 20 wt% of the whole composition and tobacco. An extruded bioactive product in the form of a sheet can be made by extruding or hot 5 melt shaping a nonaqueous composition comprising at least one thermoplastic polymer and a bioactive agent, the sheet being soluble in a users mouth and resulting in sustained release of bioactive to the user. The sheet can be in a form that may be placed in contact with the mucosa of the user, and have an average dissolution time of 5 to 50 minutes for delivering the bioactive to the user. 10 24/04/14,21671 p59a abstract speci,1
