A novel injectable composition containing propofol (2,6-diisopropylphenol) and a preparation method of the same are provided. The injectable propofol composition includes: propofol at a concentration of about 1-2% w/v, poloxamer 188 about at a concentration of 6-15% w/v, macrogol 15 hydroxystearate about at a concentration of 0.2-1% w/v, and edetate about at a con¬ centration of 0.0001-0.001% w/v.
