Carsgen Therapeutics Ltd;Shanghai Cancer Institute
发明人:
申请号:
EP16863554.8
公开号:
EP3382009A4
申请日:
2016.10.31
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
Provided is a chimeric antigen receptor-modified immune effector cell carrying a procedural death ligand 1 (PD-L1) blocking agent. Also provided is a method for secreting and expressing a PD-L1 blocking agent using the immune effector cell as a carrier to improve the anti-tumour effect of the chimeric antigen receptor-modified immune effector cell.