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СПОСОБЫ ЛЕЧЕНИЯ СВЯЗАННЫХ С FGFR3 СОСТОЯНИЙ
专利权人:
ДЖЕНЕНТЕК; ИНК. (US)
发明人:
ФРЕНЧ Дороти (US)
申请号:
RU2015102194
公开号:
RU2015102194A
申请日:
2013.07.26
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. A method of treating a disease or disorder comprising administering a therapeutically effective amount of an antagonist to an individual FGFR3, if it has been found that the individual is characterized by higher contents of biomarker FGFR3.2. A method of treating a disease or disorder in an individual, the method comprising: determining that a sample from an individual contains elevated concentrations biomarker FGFR3, and administering an effective amount of an antagonist FGFR3 subject, thereby treating the disease or narusheniya.3. A method of treating a disease or disorder in an individual comprising administering to the subject an effective amount of an antagonist of FGFR3, and treatment is based on the increase in the content of the biomarker in a sample from FGFR3 individuuma.4. The method of choice for treatment of an individual with a disease or disorder, comprising determining the contents FGFR3 biomarker and drug selection based on biomarkera.5 contents. Method individual identification with a disease or disorder, which is more or less likely to show a positive result of the treatment, comprising the antagonist of FGFR3, the method comprising: determining contents biomarker FGFR3 in a sample from the individual, wherein an increased content of a biomarker of FGFR3 in the sample indicates that the the individual is more likely to show a positive result of the treatment, comprising the antagonist of FGFR3, or a reduced content of FGFR3 biomarker indicates that the individual is less likely to show floor ozhitelny result from treatment comprising the antagonist FGFR3.6. A method of advertising antagonist FGFR3, comprising directed at a target audience1. Способ лечения индивидуума с заболеванием или нарушением, включающий введение терапевтически эффективного количества антагониста FGFR3 индивидууму, если было обнаружено, что индивидуум характеризуется повышенными содержаниями биомаркера FGFR3.2. Способ лечения заболевания или нарушения у индивидуума, причем
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