VIEIRA ERIC,LINDEMANN LOTHAR,WICHMANN JUERGEN,JAESCHKE GEORG
申请号：
NZ59681010
公开号：
NZ596810A
申请日:
2010.07.14
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
596810 Disclosed herein is a compound of general formula I, wherein the variables are defined in the specification. It has been found that the compounds of general formula (I) are metabotropic glutamate receptor antagonists. They can be used in the treatment or prevention of mGluR5 receptor mediated disorders, such as Alzheimer&rsquos disease. In one embodiment the compound is 6-(2,5-dimethyl-4-m-tolylethynyl-imidazol-1-yl)-3-methyl-3H-pyrimidin-4-one.
