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Benzamide Compounds Useful as Histone Deacetylase Inhibitors
专利权人:
AstraZeneca AB
发明人:
Stokes, Elaine Sophie Elizabeth,Turner, Andrew,Andrews, David Michael,Waring, Michael James
申请号:
NO20081582
公开号:
NO340878B1
申请日:
2008.04.01
申请国别(地区):
NO
年份:
2017
代理人:
摘要:
The invention concerns benzamide compounds of formula (I), wherein R1 is a C-linked pyrazole ring, which is optionally substituted by one or more groups selected from C1-4alkyl, C3-4cycloalkyl, C1-4alkoxy and C3-4cycloalkoxy; or a pharmaceutically acceptable salt or pro-drug form thereof. The invention also concerns processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumors or other proliferative conditions, which are sensitive to the inhibition of histone deacetylase (HDAC).
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