Jared W. Walkenhorst,Keith A. Collins,Dennis Y. Lee,Thomas G. Wilson,Thomas J. Douville,Ulrich Berlemann
申请号:
US13094512
公开号:
US20120276008A1
申请日:
2011.04.26
申请国别(地区):
US
年份:
2012
代理人:
摘要:
In one embodiment, the invention relates to a composition suitable for preparing a hydrogel useful as replacement material for all or part of a disc nucleus. The composition comprises:a curable, cross-linkable, non-immunogenic, non-toxic protein comprising a minimum of about 10% and a maximum of about 25% of the hydrogel by weighta metal contrast agent comprising a minimum of about 2% and a maximum of about 70% of the hydrogel by weight anda crosslinker comprising a minimum of about 0.1% and a maximum of about 10% of the hydrogel by weightwherein the composition has a discernable radiopacity level.