Philip E. Sanderson,Mark E. Layton,Kevin J. Rodzinak
申请号:
US13255757
公开号:
US08168652B2
申请日:
2010.03.03
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The instant invention provides for substituted naphthyridine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.