UTILISATION D'UN RÉGULATEUR DE LA CALCINEURINE 1 POUR LA FABRICATION D'UN MÉDICAMENT DESTINÉ AU TRAITEMENT DE MALADIES ASSOCIÉES À UNE ACTIVITÉ ACCRUE DU NF-KB
The present invention provides the use of a peptide comprising an amino acid sequence of SEQ ID NO:3, or the encoding nucleic acid thereof, for manufacturing medicament for treatment of diseases associated with increased NF-κB activity. The peptide can interact with IKB and influence phosphorylation of IKB in the tyrosine at position 42, thereby inhibiting the signal pathway of NF-κB.