Disclosed herein is a dressing composition comprising a bisphosphonate, or a pharmaceutically acceptable salt thereof, covalently bound to a polymer wherein, when the dressing is contacted with a wound, substantially all of the bisphosphonate remains with the dressing and is unable to enter the wound tissue. Also disclosed is a method for producing said dressing composition, and the use of a matrix metalloproteinase (MMP) inhibitor covalently bound to a polymer in the manufacture of a dressing composition for the treatment of a disease state responsive to selective inhibition of a MMP within a wound fluid.
