Indiana University Research & Technology Corporation
发明人:
申请号：
EP16796931.0
公开号：
EP3297623A4
申请日:
2016.05.05
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
Methods for targeting apurinic/apyrimidinic endonuclease1/redox effector factor 1 (APE1/Ref-1) are disclosed. More particularly, methods for inhibiting APE1/Ref-1 and hypoxia-mediated signaling for decreasing survival and invasion of tumor cells exposed to hypoxic conditions are disclosed.
