THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH;THE SCRIPPS RESEARCH INSTITUTE
发明人:
Weijun Shen,Pengyu Yang,Huafei Zou,Peter G. Schultz
申请号:
US16000829
公开号:
US20180344812A1
申请日:
2018.06.05
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Methods and compositions are provided for extending the half-life of a therapeutic agent. A modified therapeutic agent (mTA) comprises a therapeutic agent, a staple, and a half-life extending molecule. The mTAs disclosed herein may be used to treat a disease or a condition in a subject in need thereof.