TECHNISCHE UNIVERSITÄT MÜNCHEN - KLINIKUM RECHTS DER ISAR;TECHNISCHE UNIVERSITÄT MÜNCHEN
发明人:
WURZER, Alexander Josef,WESTER, Hans-Jürgen,EIBER, Matthias Johannes
申请号:
SG11202000725W
公开号:
SG11202000725WA
申请日:
2018.07.30
申请国别(地区):
SG
年份:
2020
代理人:
摘要:
The present invention relates to a ligand-SIFA-chelator conjugate, comprising, within in a single molecule three separate moieties: (a) one or more ligands which are capable of binding to a disease-relevant target molecule, (b) a silicon-fluoride acceptor (SIFA) moiety which comprises a covalent bond between a silicon atom and a fluorine atom, and (c) one or more chelating groups, optionally containing a chelated nonradioactive or radioactive cation.