use of oral heparin preparations to treat urinary tract diseases and disorders. It is an improved method for treating dysfunctional lower urinary tract epithelium (lude) or a ludic disease, condition or syndrome, including interstitial cystitis which comprises the step of orally administering a pharmaceutically effective amount of the step of orally administering an amount pharmaceutically effective heparin therapy to a patient in need of treatment for lupus or a lupus-related disease, condition or syndrome. heparin may be administered along with an amount of a penetration enhancer that is sufficient to result in a concentration of heparin tissue that is sufficient to treat lude or a lude-associated disease, condition or syndrome. A suitable penetration enhancer is sodium n- [8 - (- 2-hydroxybenzoyl) amino] caprylate. The method may further provide for the administration of at least one additional pharmaceutical composition to treat a disorder or a disorder associated with the disorder. The invention further includes a pharmaceutical composition which comprises: (1) an amount of heparin which is pharmaceutically sufficient for the treatment of lupus or a lupus-associated disease, condition or syndrome； and (b) at least one filler, excipient or carrier； wherein the pharmaceutical composition is formulated for the treatment of lude or a lude-associated disease, disorder or syndrome.uso de preparações de heparina oral para tratar doenças e afecções do trato urinário. trata-se de um método aperfeiçoado para tratar epitélio disfuncional do trato urinário inferior (lude) ou uma doença, afecção ou síndrome associada a lude, incluindo cistite intersticial que compreende a etapa de administrar oralmente uma quantidade farmaceuticamente eficaz de etapa de administrar oralmente uma quantidade farmaceuticamente eficaz de heparina a um paciente que necessita de tratamento para lude ou uma doença, afecção ou síndrome associada a lude. a heparina pode ser administrada junto a uma
