Disclosed is a hydrolyzate comprising at least one milk protein hydrolyzed with at least one proteolytic enzyme that cleaves preferentially at a glutamic acid or aspartic acid residue and that cleaves one or more immunological determinants present in the protein, the hydrolyzate comprising at least a beta lactoglobulin hydrolyzed in the region between amino acids 55-98, the hydrolyzate having reduced immunogenicity in a subject predisposed to having an immune reaction to the protein wherein at least one proteolytic enzyme is an endopeptidase, and wherein the endopeptidase is not one having the amino acid sequence 1 S V I G S D D R T R V T N T T A Y P Y R A I V H I S S S I G 31 S C T G W M I G P K T V A T A G H C I Y D T S S G S F A G T 61 A T V S P G R N G T S Y P Y G S V K S T R Y F I P S G W R S 91 G N T N Y D Y G A I E L S E P I G N T V G Y F G Y S Y T T S 121 S L V G T T V T I S G Y P G D K T A G T Q W Q H S G P I A I 151 S E T Y K L Q Y A M D T Y G G Q S G S P V F E Q S S S R T N 181 C S G P L A V H T N G V Y G G S S Y N R G T R I T K E V 211 F D N L T N W K N S A Q
