Lee D. Arnold,Qun-Sheng Ji,Elizabeth Buck,John D. Haley,Mark J. Mulvihill
申请号:
US12072269
公开号:
US08575164B2
申请日:
2008.02.25
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Methods and compositions for treating tumors or tumor metastases in a patient, comprising administering to the patient simultaneously or sequentially (a) a therapeutically effective amount of an anti-cancer agent and (b) an IGF1R inhibitor compound of Formula I, with or without additional agents or treatments, such as other anti-cancer drugs or radiation therapy. Suitable IGF1R inhibitor may be represented by Formula I:wherein X1, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein.