FRED HUTCHINSON CANCER RESEARCH CENTER;BLAZE BIOSCIENCE, INC.
发明人:
GIRARD, EMILY JUNE,CORRENTI, COLIN,OLSON, JAMES,NAIRN, NATALIE WINBLADE,GEWE, MESFIN MULUGETA,MEHLIN, CHRISTOPHER,CROOK, ZACHARY,STRONG, ROLAND,PRESNELL, SCOTT RONALD
申请号：
CA3033004
公开号：
CA3033004A1
申请日:
2017.09.09
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Peptides that are stable to denaturation and degradation by reducing agents, proteases, temperature, and low pH environments are disclosed. Pharmaceutical compositions and uses for peptides, peptide- active agent conjugates, and peptide-detectable agent conjugates comprising such peptides are also disclosed. Peptide compositions, peptide conjugate compositions, and pharmaceutical compositions can be formulated for various routes of delivery, such as oral delivery, and for deliver to various compartments of the body. Peptides of this disclosure are stable and display enhanced pharmacokinetics after such delivery.
