COMPOSÉ POUR AMÉLIORER LE COUPLAGE DU COMPLEXE TRPV4-KCA2.3 ET APPLICATIONS ANTI-HYPERTENSIVES DUDIT COMPOSÉ

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专利权人:

Jiangnan University

发明人:

MA, Xin,HE, Dongxu,TANG, Chunlei,ZHANG, Peng,CHEN, Zhen,CAI, Yanfei

申请号：

EP17904901

公开号：

EP3556747A4

申请日:

2017.05.12

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

The applicant provides a compound for enhancing the space coupling degree of an endothelial cell ion channel complex TRPV4- KCa2.3 and anti-hypertension applications thereof. By finding the structural domains of the interacting sites of the endothelial cell ion channel complex TRPV4-KCa2.3, a compound with specificity which can act at the two interacting sites is prepared in the present invention. It is found that the compound can enhance the space coupling degree of the TRPV4-KCa2.3 complex and has great significance for the research and development of anti-hypertension drugs.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/