THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY- ACADEMIC COOPERATION FOUNDATION;RESEARCH & BUSSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
发明人:
Mi-La CHO,Sung-Hwan PARK,Seung-Ki KWOK,Jong-Young CHOI,Seung-Hun LEE,Hyeon-Beom SEO,Young-Mee MOON,Jin-Sil PARK,Min-Jung PARK
申请号：
US15563435
公开号：
US20180140681A1
申请日:
2015.03.31
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present disclosure relates to a composition for preventing or treating an autoimmune disease, in which the composition includes Ssu72 as an active ingredient. According to the present invention, Ssu72 has an effect of effectively inhibiting STAT3 activity, thereby effectively preventing and treating, ultimately, an immune disease, and preferably, STAT3-mediated diseases through an action capable of inhibiting the expression of inflammatory cytokines when Ssu72 is overexpressed and simultaneously promoting the expression of IL-4 and IL-10, which are factors associated with immunoregulatory T cells.
