Tsafi Peery,Michael B. Mathews,Mainul Hoque,Hartmut M. Hanauske-Abel
申请号:
US14082346
公开号:
US20140073685A1
申请日:
2013.11.18
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Provided are methods for treating a NAD comprising administering to a patient suffering from a NAD a composition comprising an eIF5A inhibitor compound in an amount effective to prevent intracellular hypusination of eIF5A, whereby gene expression of NMD-susceptible mRNA is increased.