Shin Miyakawa,Masatoshi Fujiwara,Yoshikazu Nakamura,Kenji Kadomatsu,Ping Mu
申请号：
US14646104
公开号：
US09506070B2
申请日:
2013.11.21
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention provides an aptamer binding to midkine and capable of forming a potential secondary structure represented by the formula (I):whereinX1, X2, X5 and X6 are the same or different and each is one or two nucleotides selected from the group consisting of A, G, C, U and T, or a bond,X1 and X6, and X2 and X5 each form a Watson-Crick base pairs, andX3 and X4 are the same or different and each is a nucleotide selected from A, G, C, U and T.
