MATRICE CONTINUE DANS LAQUELLE DES PARTICULES OSTEOCONDUCTRICES SONT DISPERSEES, PROCEDE DE FORMATION DE CETTE MATRICE ET PROCEDE DE REGENERATION OSSEUSE A L'AIDE DE CETTE MATRICE
LAMBERTI, FRANCIS VINCENT,HILL, RONALD STEWART,MACMILLAN, ADAM,AHN, EDWARD,SCHLOSSBERG, BRIAN,CAPISTRON, STEPHEN,LLOYD, WILLIAM H.
申请号:
CA2860227
公开号:
CA2860227C
申请日:
2012.12.20
申请国别(地区):
CA
年份:
2020
代理人:
摘要:
The present disclosure provides compositions useful in regeneration of connective tissue, particularly bone. The compositions comprise a continuous matrix formed of a polypeptide crosslinked with a second polymer and further comprise particles of a porous, osteoconductive material dispersed in the continuous matrix. The composition can be provided in a dehydrated form. The disclosure further provides methods of preparing the composition in a clinically useful form, methods of using the composition in regenerating bone, and kits including the composition.