A composition which includes oxyntomodulin and polyethylene glycol polymer (PEG polymer) linked via a reversible linker such as 9-fluorenylmethoxycarbonyl (Fmoc) or 2-sulfo-9-fluorenylmethoxycarbonyl (FMS) is disclosed. Pharmaceutical compositions comprising the reverse pegylated oxyntomodulin and methods of using same are also disclosed.<;p>;La solicitud describe conjugados que aumentan la vida media bioló;gica de la proteí;na oxintomodulina, mediante la adició;n de los enlazadores 9-FLUORENILMETOXICARBONILO O 2-SULFO-9-FLUORENILMETOXICARBONILO.<;/p>;