Cid-Nunez, Jose Maria,Trabanco-Suarez, Andres Avelino
申请号：
AU2006259020
公开号：
AU2006259020C1
申请日:
2006.06.16
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
This invention concerns novel substituted tetracyclic tetrahydrofuran derivatives containing a cyclic amine side chain with binding affinities towards dopamine receptors, in particular dopamine D receptors, towards serotonin receptors, in particular 5-HT and 5-HT receptors, and pharmaceutical compositions comprising the compounds according to the invention, the use thereof as a medicine, in particular for the prevention and/or treatment of a range of psychiatric and neurological disorders, in particular certain psychotic, cardiovascular and gastrokinetic disorders and processes for their production. The compounds according to the invention can be represented by general Formula (I) and comprises also a pharmaceutically acceptable acid or base addition salt thereof, an -oxide form thereof or a quaternary ammonium salt thereof, wherein all substituents are defined as in Claim 1.
