Inhibitors of BCR-ABL mutants and use thereof

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专利权人:

THE REGENTS OF THE UNIVERSITY OF MICHIGAN

发明人:

Matthew B. Soellner,Sameer Phadke

申请号：

US15685707

公开号：

US10196378B2

申请日:

2017.08.24

申请国别(地区):

US

年份:

2019

代理人:

摘要：

Inhibitor compounds of Bcr-Abl and Bcr-Abl mutants including Bcr-Abl T315I mutant protein are disclosed. Compositions comprising the inhibitor compounds and methods of using the compounds in the treatment of leukemia such as chronic myelogenous leukemia are also disclosed.

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