UNIVERSITY OF SOUTH FLORIDA;The United States Government as Represented by the Department of Veterans Affairs
发明人:
SHYAM S. MOHAPATRA,SUBHRA MOHAPATRA
申请号:
US16330858
公开号:
US20190216855A1
申请日:
2017.09.19
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention pertains to a strategy of selectively targeting oncolytic virotherapy, using either naturally occurring or genetically modified viruses by packaging them in mesenchymal stem cells (MSCs). The present invention concerns MSCs, compositions comprising the MSCs, and methods of using the MSCs for treatment of cancer and for lysing or inducing apoptosis of cancer cells in vitro or in vivo.