您的位置: 首页 > 农业专利 > 详情页

PROCESSOS PARA PRODUZIR MICROFOLÍCULOS CAPILARES E PAPILAS DE NOVO E RESPETIVA UTILIZAÇÃO EM TESTES IN VITRO E EM IMPLANTES IN VIVO
专利权人:
TECHNISCHE UNIVERSITAET BERLIN
发明人:
GERD LINDNER,ROLAND LAUSTER
申请号:
PT09724502
公开号:
PT2274419E
申请日:
2009.03.23
申请国别(地区):
PT
年份:
2012
代理人:
摘要:
The present invention relates to a method for producing de novo papillae, in which dermal hair papilla fibroblasts (DPFs) are isolated from a dermal papilla (DP) of a mammal hair follicle, subsequently expanded, and finally condensed into cell aggregates that exhibit the size and shape of the physiological DP, wherein said DPFs are differentiated in ultra-low attachment culture vessels in a cell concentration per vessel surface of 1.000 to 100.000 DPFs/cm 2 . The invention also relates to a method for producing hair microfollicles by co-culturing the de novo papillae with another cell population of the hair follicle in the ultra-low attachment culture vessels. Object of the invention are also the de novo papillae and the hair microfollicles produced by the aforementioned methods. The de novo papillae and hair microfollicles can be used as implants for treating reduced hair conditions, and for in vitro testing hair-modulating effects or toxic effects of substances.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充