STEWART, ANDREW F.,ACKEIFI, COURTNEY,WANG, PENG,DEVITA, BOB
申请号:
CA3086925
公开号:
CA3086925A1
申请日:
2019.01.05
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Disclosed herein are methods of increasing cell proliferation in a population of pancreatic beta cells. Also disclosed are methods of treating a subject for a condition associated with insufficient insulin secretion. Also disclosed is a composition comprising a DYRK1 A inhibitor and a GLP1R agonist. The disclosure further describes a method of regenerating pancreatic beta cells in a transplant patient.