The present invention is related to a thermostable solid composition comprising nanosized micelles of a poorly soluble chemical substance, such as a biologically active substance, dissolved in an auxiliary material, said micelles being embedded in a water soluble carrier. The invention is further related to a process for preparing said solid composition and to pharmaceutical dosage forms prepared from this composition.本發明涉及耐熱型固體組合物,其包含溶解於輔助材料中的難溶性化學物質例如生物學活性物質的奈米級膠束,所述膠束包埋在水溶性載體中。本發明進一步涉及用於製備所述固體組合物的方法以及由這種組合物製備的藥物劑型。